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Virginia Hargest, Ph.D., is a Technical Advisor in Ice Miller’s Intellectual Property Practice Group. In this capacity, she advises the team on technical requirements to be used in U.S. and foreign patent applications, technical components for patent interference and litigation proceedings, and technical research and analysis with respect to matters pending before the United States Patent and Trademark Office.

She is a skilled molecular biologist and virologist with more than eight years of experience in microbiology and host pathogenesis. Her doctoral research focused on elucidated cellular and viral mechanisms of the regulation and induction of epithelial-mesenchymal transition during human astrovirus infection. Prior to joining the firm, Virginia was a Post-Doctoral Fellow and a Lead Researcher at St. Jude Children’s Research Hospital.

Virginia Hargest does not provide legal services.
Published In

•    Co-Author, Astrovirus replication is dependent on induction of double membrane vesicles through a PI3K-dependent, LC3-independent pathway. Journal of Virology, 2023
•    Co-Author, Indoleamine 2,3 Dioxygenase-1 Regulates Cell Permissivity to Astrovirus Infection. Mucosal Immunology, 2023
•    Co-Author, Human Astrovirus VA1 Encephalitis in Pediatric Patients With Cancer: Report of 2 Cases and Review of the Literature. Journal of Pediatric Infectious Disease Society, 2022
•    Author, Astrovirus-Induced Epithelial-Mesenchymal Transition via Activated TGF-β Increases Viral Replication. PLOS Pathogens, 2022
•    Co-Author, Human Astroviruses: A Tale of Two Strains. Viruses, 2021
•    Author, Nitazoxanide Inhibits Astrovirus Replication In Vitro and In Vivo. Journal of Virology, 2020
•    Co-Author, Astroviruses (Astroviridae) in the Encyclopedia of Virology Fourth Edition. Elsevier, 2018
•    Co-Author, Astrovirus Biology and Pathogenesis Astrovirus Biology and Pathogenesis. Annual Review of Virology, 2017
•    Co-Author, Astrovirus Pathogenesis Astrovirus Pathogenesis. MDPI – Viruses, 2017

Speaking Engagements
•    Speaker, Collaborative Influenza Vaccine Innovation Centers (Bethesda, MD), “The Effects of COBRA Vaccination on Influenza Transmission Dynamics in the DIO Ferret Model” 2022 
•    Speaker, American Society of Virology (Madison, WI), “Astrovirus-Induced Epithelial-Mesenchymal Transition via Activated TGF-β Increases Viral Replication” 2022 
•    Speaker, Center for Influenza Vaccine Research for High-Risk Populations (Athens, GA), “Live Attenuated Influenza Vaccination in Models of Obesity” 2022 
•    Poster, Viruses and Cells Gordon Research Conference and Seminar (Lucca, Tuscany, Italy), “Human Astrovirus Induced Epithelial-Mesenchymal Transition Is Regulated by MicroRNA-487A” 2019
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