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Ming He, Ph.D. prepares, files and prosecutes applications in the chemical and pharmaceutical industries. Ming also conducts due diligence, patent analyses and freedom-to-operate analyses.

Prior to becoming a patent agent, Ming served as a senior process chemist at a pharmaceutical company. He discovered and developed efficient, safe and cost-effective synthetic routes for organic compounds. In addition, Ming developed a manufacturing process from a lab synthesis to GMP production.

He previously worked as a senior research assistant for Unilever, where he identified and isolated bioactive ingredients from traditional Chinese medicinal plants as well as developed efficient chemical assays for screening antibacterial components.

Ming was a postdoctoral fellow in Professor Amos B. Smith’s group at University of Pennsylvania, working on the synthesis of complex natural products, e.g., revised structure of Lituarine C and (+)-Neopeltolide. Ming obtained his Ph.D degree in 2008 at University of California, Santa Barbara under supervision of Professor Jeffrey W. Bode. His doctoral research focused on the development of novel methodologies to synthesize heterocyclic molecules via N-heterocyclic carbene (NHC)-catalyzed redox reactions of alpha-functionalized aldehydes.

Firm Publications
Published In
  • He, M.; Rommel, M.; Bode, J.W. “Formal Synthesis of (±)-Clausenamide by NHC-Catalyzed γ-Lactam Formation”, Heterocycle.s 2012, 86, 1689-1696.
  • He, M.; Beahm, B. J.; Bode, Jeffrey W. “Chiral N-Heterocyclic Carbene Catalysis under Aqueous Conditions: Enantioselective Hetero-Diels-Alder Reactions with alpha-Chloroaldehyde Bisulfite Salts”, Org. Lett. 2008, 10, 3817-3820.
  • He, M.; Bode, J.W. “Enantioselective, NHC-Catalyzed Bicyclo-Lactam Formation from Enals and Unsaturated N-Sulfonyl Ketimines”, J. Am. Chem. Soc., 2008, 130, 418-419.
  • He, M.; Uc, G. J.; Bode, J.W. “Chiral N-Heterocyclic Carbene Catalyzed, Enantioselective Oxodiene Diels-Alder Reactions with Low Catalyst Loadings”, J. Am. Chem. Soc., 2006, 128, 15088-15089.
  • He, M.; Struble, J.R.; Bode, J.W. “Highly Enantioselective Azadiene Diels-Alder Reactions Catalyzed by Chiral N-Heterocyclic Carbenes”, J. Am. Chem. Soc. 2006, 128, 8418-8420
  • He, M.; Bode, J.W. “Catalytic Synthesis of beta-Lactams via Direct Annulations of Enals and N-Sulfonylimines”, Org. Lett. 2005, 7, 3131-3134.
  • He, M.; Hu, C-Q. “Studies on the Chemical Components of Clematis Chinesis”, Acta Pharmaceutica Sinica, 2001, 36, 278-280.
  • He, M.; Hu, C-Q. “Studies on the Chemical Components of Clematis Chinesis”, Journal of Chinese Pharmaceutical Sciences, 2001, 10, 180-182.
  • He, M.; Hu, C-Q. “GC-MS Analysis of the Volatile Constituents of Radix Clematidis”, Chinese Traditional and Herbal Drugs, 1999, 30, 811-812.
  • He, M.; Hu, C-Q. “Research Development on Phytoestrogens”, Chinese Traditional Patent Medicine, 1999, 21, 42-45.
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